Growth Factor I, insulin sensitivity, life extension
Andrzej Bartke, a researcher in geriatrics, and his colleagues at Southern Illinois University in Springfield, are closing in on the genetic basis for and biochemical/endocrine prevention of aging in mammals .
For years it has been observed that calorie restriction could enhance longevity in rats and other animals (research history) but the mechanisms behind this effect were unknown.
In a 2006 article in the Proceedings of the National Acadamy of Sciences , they write
Continue reading“there is considerable evidence that reduced secretion of insulin-like growth factor I and insulin are among the mechanisms that mediate the effects of Calorie Restriction (CR) on aging and longevity in mammals.”