Author: ellen

Recent research on Alzheimer’s Disease

A quick survey of some of the more interesting research on Alzheimer’s Disease recently:

I. Causes and Disease Mechanisms
Alzheimer’s Disease Could Be A Third Form Of Diabetes

Science Daily Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer’s memory loss could be due to a novel third form of diabetes.

Now scientists at Northwestern University have discovered why brain insulin signaling — crucial for memory formation — would stop working in Alzheimer’s disease. They have shown that a toxic protein found in the brains of individuals with Alzheimer’s removes insulin receptors from nerve cells, rendering those neurons insulin resistant. ..

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Javascript’s parseInt

Javascript is a loosely typed language, which means it is possible to define a variable without specifying what type of data it holds (string, integer, floating point, etc.). This can cause problems if you think a particular value is a number when in fact it is a string. A string must be converted to a number to use it in calculations.

For example, when working with SCORM elearning software, scoring and performance data is stored in a Learning Management System as strings. If you need to do calculations with the data after retrieving it, the string data must be converted to integers or floating point type.

The parseInt() function can be used for this purpose. It parses a string and returns an integer. However use of the function without understanding the details can lead to unexpected results. If your string begins with a zero, the number will be evaluated in octal instead of decimal system. In Octal, 08, 09 are not valid numbers, and 010, 011, etc. will not represent the same values as they would in decimal system.

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Interesting DNA, RNA research you might have missed

There is much happening in genetics it’s hard to know where to start listing the highlights. Here are some of the more interesting items I’ve come across recently:

Did DNA replication evolve twice independently?
by Leipe DD, Aravind L, Koonin EV. in
Nucleic Acids Res. 1999 Sep 1;27(17):3389-401.

DNA replication is central to all extant cellular organisms.
principal proteins involved in transcription and translation, which are highly conserved in all divisions of life.
We performed detailed sequence comparisons of the proteins that fulfill indispensable functions in DNA replication and classified them.

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