Macromedia vector applications- Fireworks and Freehand - all seem to share problems with the Wacom tablets and have for quite a while. It used to be that the problems with Freehand and Fireworks could be fixed by setting the button on the pen tool to be ignored, but now that does not do the trick. Apparently Macromedia is aware of this as an "emerging" issue, but has not yet fixed it. I hope they do, since Fireworks MX 2004 is nearly unusable for those of us who are addicted to the tablet.

Update:
Post on the Macromedia forums:

"Download Wacom tablet driver version 4.7.6-3 from the following URL:
ftp://ftp.wacom-europe.com/pub/Mac/mac_x_4.7.6-3_en.sit.hqx

This is an older version of the Wacom Tablet software. To work around the issues discussed in this thread, uninstall the newer Wacom Tablet software, then download version 4.7.6-3 from the ftp URL provided and install it. "
- Marisa
Macromedia Fireworks, QA